منابع مشابه
Electrophysiology of neurosecretory cells from the pituitary intermediate lobe.
One of the goals in studying the electrical properties of neurosecretory cells is to relate their electrical activity to the process of secretion. A central question in these studies concerns the role of transmembrane calcium ion flux in the initiation of the secretory event. With regard to the secretory process in pituitary cells, several research groups have addressed this question in vitro u...
متن کاملHormone of Middle Lobe of Pituitary Melanocyte Stimulating Hormones
The hormones secreted by intermediate lobe or middle lobe of pituitary gland are called melanocyte stimulating hormones or MSH. POMC is the precursor molecule which is cleaved by proteases to give ACTH and β-lipotropin. The ACHT is further cleaved to β-MSH which has 13 amino acids. There is also α-MSH which is present in larger quantities. Amino acids 11-17 of β-MSH are common to both α-MSH and...
متن کاملRegulation of pro-opiomelanocortin synthesis by dopamine and cAMP in the amphibian pituitary intermediate lobe.
The modulation of pro-opiomelanocortin (POMC) synthesis in Xenopus laevis pituitary intermediate lobe (IL) during background adaptation and the role of dopamine and cAMP in mediating this effect were examined. Neurointermediate lobes (NILs) were pulselabeled in vitro with [3H]arginine and analyzed for POMC synthesis by acid-urea gel electrophoresis. After black background adaptation of the anim...
متن کاملXlvi. the Oxytocic Hormone of the Posterior Lobe of the Pituitary Gland
IN Part V [Gulland and Randall, 1935] it was shown that the molecule of the oxytocic hormone certainly contains one, and may possibly contain two, oxidation-reduction systems, although the existence of the second is not definitely established. The present communication describes the actions on the hormone of some oxidising and reducing agents, which were studied in the hope that they might thro...
متن کاملRelease of alpha-MSH from the in vitro superfused neuro-intermediate lobe of the pituitary of the rat by antidiuretic hormone.
The effect of antidiuretic hormone (ADH) on the release of immunoreactive alpha-melanocyte stimulating hormone (alpha-MSH) from the superfused neurointermediate lobe of the pituitary of the normal Wistar and Brattleboro (diabetes insipidus) rat was studied in vitro. In control experiments, there was usually an initial peak, after which alpha-MSH release fell exponentially over the course of the...
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ژورنال
عنوان ژورنال: Quarterly Journal of Experimental Physiology and Cognate Medical Sciences
سال: 1941
ISSN: 0033-5541
DOI: 10.1113/expphysiol.1941.sp000847